Researchers at the University of Utah are conducting an early feasibility study to determine if implanted micro-electrodes can record neural signals and provide sensory feedback to individuals with limb amputations. According to a clinical trial record, the study investigates the ability of the HAPTIX System to control an upper-extremity prosthesis while providing cutaneous touch and muscle proprioceptive feedback.
The study involves the implantation of percutaneous Utah Slanted Electrode Arrays (pUSE
As) into residual peripheral arm nerves. Investigators aim to assess whether recording motor information from these electrodes can allow for the control of artificial limbs with multiple moving parts, such as the wrist and individual digits.
In addition to recording motor intents, the study explores using microstimulation via the electrode arrays to evoke sensory perceptions. The HAPTIX System intends to use a combination of electromyography (EMG), neural recording, and nerve stimulation to assist amputees with activities of daily living using a sensorized, motorized prosthesis.
The research focuses on patients with unilateral or bilateral traumatic or elective upper-extremity amputations at the transradial level. Eligible participants must be between the ages of 18 and 65. The study is currently recruiting and is based at the University Orthopaedic Center in Salt Lake City, Utah.
The study is an interventional trial designed to measure action potentials in millivolts arising from axons surrounding the electrode tips. The project is sponsored by the University of Utah and is expected to reach primary completion by December 2028.
